MiGRACAPS® –natural and effective

MiGRACAPS® may reduce the frequency of migraines.

MiGRACAPS® capsules contain Tanacetum parthenium (otherwise known as Feverfew).

Feverfew has been traditionally used in herbal medicine to assist in the management of fever and headaches. It may also assist with pain associated with inflammatory conditions such as arthritis as well as pain associated with menstruation (period pain).

Feverfew has been used for centuries as a relaxant to help lower the frequency and calm the severity of symptoms associated with migraine headaches. Today, Feverfew is most often taken as a preventative measure against the onset of migraine and many other inflammatory conditions.

Many studies have found Feverfew administration to result in a reduction in the severity of symptoms associated with migraine, as compared to placebo. The mode of action of Feverfew may involve the inhibition of platelet aggregation and prostaglandin synthesis. Feverfew has anti-inflammatory and vasodilatory properties that may work to reduce blood vessel spasms and inhibit the release of inflammatory substances. Feverfew may benefit many conditions involving inflammation.

Feverfew is suitable to take in the long term to help minimise the frequency of migraine attack and, in the short term, to help ease the severity of symptoms. Feverfew can be taken for many inflammatory conditions ranging from inflammatory skin conditions to inflammation of body joints.

Mode of Action

Inhibits serotonin release from platelets
Inhibits platelet aggregation
Reduces blood vessel constriction
Inhibits formation and release of inflammatory substances

Migraine is the result of an inflammatory phenomenon which occurs in the blood vessels surrounding the brain. Platelets in migraine sufferers have been demonstrated to aggregate (clump) more readily than in others. This occurs both spontaneously and when exposed to serotonin and catecholamines such as adrenaline.

If the blood levels of catecholamines rise, serotonin, which is a potent vasoconstrictor, is released. This causes platelet aggregation and vasospasm (spasm of blood vessels) which then leads to an interruption of blood flow to the brain. This is then followed by a 'rebound' vasodilation (widening of the blood vessels) and the release of pain inducing substances. This sequence of events leads to the characteristic symptoms associated with a migraine headache.

Sesquiterpene lactones, particularly parthenolide, are thought to be the main active constituents of Feverfew. They inhibit platelet aggregation and the secretion of serotonin which can trigger the vasoconstriction leading to a migraine.

Each capsule contains Tanacetum parthenium powder equivalent to 520mg dry flowering herb top.

MiGRACAPS® is Gluten-free and contains no artificial flavourings or colours. It is also suitable for vegetarians.

Take one capsule twice a day for the first 4 weeks.
After the first four weeks the dosage may be reduced to one capsule once a day.

The beneficial effects of MiGRACAPS® may take 2-4 weeks to occur.

Additional benefit may be obtained by using Migrastick® to assist with rapid relief of migraine at the first sign of a migraine headache.